Week 12 NFL Betting Odds: Vegas Lines & Game Predictions

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There weren’t many surprises in the NFL last week. Favorites went 12-2 overall and 9-5 against the spread. Only the Panthers and Redskins lost as favorites. Road favorites did particularly well, going 4-0 both straight up and against the spread.

At this point in the season we have a handful of teams that are virtual locks to make the playoffs.  The Patriots, Ravens, 49ers, and Packers would need to have a complete meltdown to miss out on the postseason. Let’s take a look at this week’s betting odds.

Week 12 NFL Point Spreads, Totals & Free Picks

Thursday night we finally get a meaningful game with the Colts at Texans. Both teams are 6-4, tied for the lead in the AFC South. The winner will take a huge step in securing a playoff spot.

The Packers at 49ers should be a great game, but it shouldn’t have much impact on the season overall. Both teams are comfortably slotted in the playoff picture.  Teams that really need a win include the Rams and Raiders, who are currently projected to miss out on the post season.  They’ll be hoping for losses by the Bills, Texans, Seahawks, or Vikings in the comping weeks (Minnesota is on a bye this week).

The table below features all of the NFL odds for this week in the season. Check up-to-the-minute odds changes on our live odds page. You’ll also find a free betting preview link to each game as they become available. For higher-rated free NFL picks, click here.

Week 12 NFL Odds (From 5Dimes)

Date/Time Matchup Spread Total Preview
Thu Nov 21st
9:20 PM
Indianapolis Colts
Houston Texans
3.5
-3.5
45.5 Preview
Sun Nov 24th
2:00 PM
Miami Dolphins
Cleveland Browns
10.5
-10.5
44.5 Preview
Sun Nov 24th
2:00 PM
Denver Broncos
Buffalo Bills
3.5
-3.5
37.5 Preview
Sun Nov 24th
2:00 PM
Pittsburgh Steelers
Cincinnati Bengals
-6.5
6.5
39 Preview
Sun Nov 24th
2:00 PM
New York Giants
Chicago Bears
6.5
-6.5
40 Preview
Sun Nov 24th
2:00 PM
Oakland Raiders
New York Jets
-3
3
46.5 Preview
Sun Nov 24th
2:00 PM
Carolina Panthers
New Orleans Saints
9.5
-9.5
47 Preview
Sun Nov 24th
2:00 PM
Tampa Bay Buccaneers
Atlanta Falcons
4
-4
51 Preview
Sun Nov 24th
2:00 PM
Detroit Lions
Washington Redskins
-3.5
3.5
41.5 Preview
Sun Nov 24th
2:00 PM
Seattle Seahawks
Philadelphia Eagles
1
-1
48 Preview
Sun Nov 24th
5:05 PM
Jacksonville Jaguars
Tennessee Titans
3
-3
42 Preview
Sun Nov 24th
5:25 PM
Dallas Cowboys
New England Patriots
6.5
-6.5
45 Preview
Sun Nov 24th
9:20 PM
Green Bay Packers
San Francisco 49ers
3
-3
48 Preview
Mon Nov 25th
9:15 PM
Baltimore Ravens
Los Angeles Rams
-3
3
46.5 Preview

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