Week 9 of the NFL season was one of the best ever for public bettors with every large favorite winning and covering the spread relatively easily. Books got hammered with wins against the spread by the Chiefs, Vikings, Panthers, and Patriots. The biggest “upset” to speak of came with the then-undefeated LA Rams losing at New Orleans 45-35 (the Rams did close as 2-point favorites). Let’s take a look at the lines for this week’s games.
After last week’s beating, you have to wonder if sportsbooks will over-adjust for Week 10. It certainly isn’t common to see four games with double-digit spreads, but it is not unprecedented either. The biggest spread of the week comes with the Chiefs over the Cardinals. The Chiefs have looked unstoppable against inferior opponents, so it’s no surprise they are 16.5-point favorites over the 2-6 Cardinals. Arizona is coming off of their bye week, however, it’s worth noting that underdogs of 14 points or more coming off of their bye week are just 1-5 against the spread going back to 1989.
Below you will find the latest odds for this week’s games, plus a betting preview for the matchup as they become available. Each preview give you a prediction against the spread or on the total by our staff writers. For free picks from our pros, you’ll want to visit our free NFL picks.
Line are current as of the publish date of the article, but they change frequently so the best place to compare the latest odds updates would be to see our live NFL odds here.
Week 10 NFL Odds (From 5Dimes)
| Time (TV) | Matchup | Open | Current | Total | Preview |
|---|---|---|---|---|---|
| 8:25pm (NBC) | Carolina Panthers Pittsburgh Steelers |
+5 -5 |
+4 -4 |
51.5 | Preview |
| Time (TV) | Matchup | Open | Current | Total | Preview |
|---|---|---|---|---|---|
| 1:00pm (CBS) | Buffalo Bills New York Jets |
+8 -8 |
+7.5 -7.5 |
37 | Preview |
| 1:00pm (FOX) | Atlanta Falcons Cleveland Browns |
-3.5 +3.5 |
-4.5 +4.5 |
51 | Preview |
| 1:00pm (FOX) | New Orleans Saints Cincinnati Bengals |
-4 +4 |
-4.5 +4.5 |
54 | Preview |
| 1:00pm (FOX) | Washington Redskins Tampa Bay Buccaneers |
+1 -1 |
+3 -3 |
51.5 | Preview |
| 1:00pm (CBS) | New England Patriots Tennessee Titans |
-6.5 +6.5 |
-6.5 +6.5 |
46.5 | Preview |
| 1:00pm (CBS) | Jacksonville Jaguars Indianapolis Colts |
+3 -3 |
+3 -3 |
47 | Preview |
| 1:00pm (CBS) | Detroit Lions Chicago Bears |
+7 -7 |
+6.5 -6.5 |
45 | Preview |
| 1:00pm (FOX) | Arizona Cardinals Kansas City Chiefs |
+17 -17 |
+16.5 -16.5 |
49.5 | Preview |
| 4:05pm (FOX) | Los Angeles Chargers Oakland Raiders |
-10 +10 |
-10 +10 |
50 | Preview |
| 4:25pm (CBS) | Miami Dolphins Green Bay Packers |
+10 -10 |
+10 -10 |
47.5 | Preview |
| 4:25pm (CBS) | Seattle Seahawks Los Angeles Rams |
+10 -10 |
+10 -10 |
51 | Preview |
| 8:20pm (NBC) | Dallas Cowboys Philadelphia Eagles |
+6.5 -6.5 |
+6.5 -6.5 |
43.5 | Preview |
| Time (TV) | Matchup | Open | Current | Total | Preview |
|---|---|---|---|---|---|
| 8:30pm (ESPN) | New York Giants San Francisco 49ers |
+2.5 -2.5 |
+3 -3 |
43.5 | Preview |