Week 10 NFL Betting Odds: Vegas Spreads & Totals

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The dust from Week 9 of the NFL season has settled and the playoff picture is really starting to take shape. The biggest headline is probably that the Patriots finally lost (vs the Ravens), leaving just one undefeated team in the San Francisco 49ers (8-0). The Dolphins also finally won their first game of the season by defeating the Jets, leaving the Bengals as the last winless team in the league.

Week 10 NFL Vegas Game Lines: Point Spreads & Betting Totals

Week 10 of the season is an interesting one. There are a lot of lopsided matchups (three double-digit spreads), coupled with several games that are expected to be close (five matchups with spreads of 3 or less). There aren’t many impactful matchups as far as the playoffs are concerned, but the game we’re most interested in is the Seahawks at the 49ers on Monday Night Football. ┬áThe 49ers are undefeated, but the Seahawks have looked very good lately and this will be San Fran’s toughest contest to date.

Below you will find the latest odds for this week’s games, plus a betting preview for the matchup as they become available. Each preview give you a prediction against the spread or on the total by our staff writers. For free picks from our pros, you’ll want to visit our free NFL picks.

Line are current as of the publish date of the article, but they change frequently so the best place to compare the latest odds updates would be to see our live NFL odds here.

Week 10 NFL Odds (From 5Dimes)

Date/Time Matchup Spread Total Preview
Thu Nov 7th
9:20 PM
Los Angeles Chargers
Oakland Raiders
-1
1
49 Preview
Sun Nov 10th
2:00 PM
Kansas City Chiefs
Tennessee Titans
Preview
Sun Nov 10th
2:00 PM
Buffalo Bills
Cleveland Browns
3
-3
40 Preview
Sun Nov 10th
2:00 PM
Arizona Cardinals
Tampa Bay Buccaneers
4.5
-4.5
51 Preview
Sun Nov 10th
2:00 PM
New York Giants
New York Jets
-2.5
2.5
43.5 Preview
Sun Nov 10th
2:00 PM
Atlanta Falcons
New Orleans Saints
13
-13
51 Preview
Sun Nov 10th
2:00 PM
Baltimore Ravens
Cincinnati Bengals
-10
10
45.5 Preview
Sun Nov 10th
2:00 PM
Detroit Lions
Chicago Bears
2.5
-2.5
41.5 Preview
Sun Nov 10th
5:05 PM
Miami Dolphins
Indianapolis Colts
10
-10
44 Preview
Sun Nov 10th
5:25 PM
Carolina Panthers
Green Bay Packers
5
-5
47 Preview
Sun Nov 10th
5:25 PM
Los Angeles Rams
Pittsburgh Steelers
-3.5
3.5
44 Preview
Sun Nov 10th
9:20 PM
Minnesota Vikings
Dallas Cowboys
3
-3
48 Preview
Mon Nov 11th
9:15 PM
Seattle Seahawks
San Francisco 49ers
6
-6
47 Preview

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