Week 4 of the college football season featured several upsets of top-ranked teams. #10 Utah lost to unranked USC on Friday and #15 UCF lost at Pitt. Other ranked teams losing to unranked opponents included TCU to SMU and Washington State to UCLA. Within the Top 25 there were several matchups, but they mostly went as expected. Georgia defeated Notre Dame and Auburn bet Texas A&M. The lone “upset” came in the Big Ten where #13 Wisconsin blew out #11 Michigan 35-14.
This week we get just two Top 25 matchups (Virginia at Notre Dame and USC at Washington), but there are a ton of strong games to bet on. Below you’ll find the odds for the most notable games of the week, plus a link to a betting preview from one of our writers as they become available. Be sure to check on the live college football odds as these lines are only accurate as of the publish date and are sure to change.
Weekly College Football Odds (From BetOnline)
| Time (TV) | Matchup | Spread | Total | Preview |
|---|---|---|---|---|
| 8:00 PM (ESPN) |
Navy Memphis |
+10.5 -10.5 |
55 | Preview |
| Time (TV) | Matchup | Spread | Total | Preview |
|---|---|---|---|---|
| 7:00 PM (ESPN) |
Duke Virginia Tech |
+3 -3 |
52 | Preview |
| 8:00 PM (FS1) |
#12 Penn State Maryland |
-6.5 +6.5 |
59.5 | Preview |
| 8:00 PM (CBSSN) |
San Jose State Air Force |
+19.5 -19.5 |
56 | Preview |
| 10:30 PM (ESPN) |
Arizona State #15 California |
+4.5 -4.5 |
40 | Preview |
| Time (TV) | Matchup | Spread | Total | Preview |
|---|---|---|---|---|
| 12:00 PM (N/A) |
Texas Tech #6 Oklahoma |
+26 -26 |
72 | Preview |
| 12:00 PM (ABC) |
Northwestern #8 Wisconsin |
+24 -24 |
45 | Preview |
| 12:00 PM (ESPN2) |
Middle Tennessee #14 Iowa |
+24 -24 |
52 | Preview |
| 12:00 PM (BTN) |
Rutgers #20 Michigan |
+27 -27 |
48 | Preview |
| 12:00 PM (ESPN) |
#23 Texas A&M Arkansas |
+23 -23 |
56 | Preview |
| 12:00 PM (SEC) |
Northern Illinois Vanderbilt |
+6.5 -6.5 |
54.5 | Preview |
| 12:00 PM (FS1) |
Kansas TCU |
+16 -16 |
48 | Preview |
| 12:00 PM (ESPN+) |
BYU Toledo |
-1.5 +1.5 |
60 | Preview |
| 12:00 PM (ESPNU) |
Buffalo Miami (OH) |
+1.5 -1.5 |
50 | Preview |
| 12:00 PM (CBSSN) |
Central Michigan Western Michigan |
+17 -17 |
59 | Preview |
| 3:30 PM (ABC) |
#1 Clemson North Carolina |
-26.5 +26.5 |
60.5 | Preview |
| 3:30 PM (CBS) |
Ole Miss #2 Alabama |
+35 -31 |
61.5 | Preview |
| 3:30 PM (NBC) |
#18 Virginia #10 Notre Dame |
+11.5 -11.5 |
50.5 | Preview |
| 3:30 PM (FOX) |
#21 USC #17 Washington |
+10 -10 |
59 | Preview |
| 3:30 PM (BTN) |
Indiana #25 Michigan State |
+14.5 -14.5 |
44.5 | Preview |
| 3:30 PM (NFL) |
Florida Atlantic Charlotte |
PK PK |
65.5 | Preview |
| 3:30 PM (CBSSN) |
Georgia Tech Temple |
+9.5 -9.5 |
50 | Preview |
| 3:30 PM (ACCN) |
Wake Forest Boston College |
-6.5 +6.5 |
65 | Preview |
| 3:30 PM (ESPN) |
Iowa State Baylor |
-2.5 +2.5 |
56.5 | Preview |
| 3:30 PM (ESPN2) |
Minnesota Purdue |
-1.5 +1.5 |
56.5 | Preview |
| 3:30 PM (N/A) |
Akron UMass |
-6.5 +6.5 |
64 | Preview |
| 4:00 PM (ESPNU) |
SMU USF |
-7 +7 |
60.5 | Preview |
| 5:00 PM (N/A) |
Cincinnati Marshall |
-3 +3 |
46.5 | Preview |
| 6:00 PM (ESPN+) |
ECU Old Dominion |
+2 -2 |
48.5 | Preview |
| 6:00 PM (ESPN+) |
Arkansas State Troy |
+7 -7 |
61 | Preview |
| 6:00 PM (ESPN+) |
Louisiana Georgia Southern |
-3 +3 |
59 | Preview |
| 7:00 PM (ESPN) |
Mississippi State #7 Auburn |
+11 -11 |
47 | Preview |
| 7:00 PM (ESPN2) |
UConn #22 UCF |
+42.5 -42.5 |
64.5 | Preview |
| 7:00 PM (ESPN+) |
#24 Kansas State Oklahoma State |
+5 -5 |
60 | Preview |
| 7:00 PM (ESPN+) |
South Alabama UL-Monroe |
+16 -16 |
58 | Preview |
| 7:00 PM (ESPN+) |
UTEP Southern Miss |
+25 -25 |
53 | Preview |
| 7:00 PM (ESPN+) |
UAB Western Kentucky |
-3 +3 |
46.5 | Preview |
| 7:00 PM (ESPN3) |
LA Tech Rice |
-10 +10 |
48.5 | Preview |
| 7:00 PM (PAC12) |
Stanford Oregon State |
-3.5 +3.5 |
58.5 | Preview |
| 7:30 PM (ABC) |
#5 Ohio State Nebraska |
-17.5 +17.5 |
67 | Preview |
| 7:30 PM (ACCN) |
NC State Florida State |
+6 -6 |
60 | Preview |
| 7:30 PM (SEC) |
Kentucky South Carolina |
+2 -2 |
51.5 | Preview |
| 7:30 PM (CBSSN) |
Colorado State Utah State |
+24 -24 |
72.5 | Preview |
| 8:00 PM (ESPNU) |
UNLV Wyoming |
+9.5 -9.5 |
49.5 | Preview |
| 8:00 PM (N/A) |
Fresno State New Mexico State |
-17.5 +17.5 |
67 | Preview |
| 8:00 PM (N/A) |
Houston North Texas |
+6 -6 |
59.5 | Preview |
| 10:00 PM (FS1) |
Washington State #19 Utah |
+5 -5 |
56.5 | Preview |
| 10:30 PM (ESPN) |
UCLA Arizona |
+7.5 -7.5 |
71.5 | Preview |
| 10:30 PM (ESPN2) |
Hawaii Nevada |
+2.5 -2.5 |
64.5 | Preview |