The Kansas City Chiefs host the Denver Broncos on Thursday, September 17 to kick off Week 2 NFL action. The Broncos have won six straight meetings in this series, all of which have come since Peyton Manning took over as their starting quarterback.

Denver (1-0) survived a defensive battle with Baltimore in its opener with a 19-13 home victory as 4.5-point favorites. Kansas City (1-0) jumped out to a big lead early at Houston last week and held on for a 27-20 win.

Kickoff inside Arrowhead Stadium is scheduled for 8:25 EST Thursday night with CBS providing the television coverage. Taking a look at the odds in Las Vegas, I find Kansas City listed as a 3-point favorite over Denver with a total set of 42 points.

My Early Lean: Chiefs -3

The Kansas City Chiefs will be highly motivated to put an end to their 6-game losing streak to the Denver Broncos in this series. They know that if they want to win the division, it’s going to come down to beating the Broncos. I believe they now have the pieces to do so, and I agree with this line moving from a pick ’em all the way to Chiefs -3.

Kansas City was very impressive in its Week 1 win against Houston. It jumped out to a 27-9 lead by halftime and held on for a 27-20 win in a game that was a bigger blowout than the final score would indicate. Alex Smith went 22 of 33 passing for 243 yards with three touchdowns in the win. He found tight end Travis Kelce six times for 106 yards and two scores. New No. 1 receiver Jeremy Maclin had a solid debut with five grabs for 52 yards.

The Chiefs certainly have one of the best defenses in the NFL this season. They got back linebacker Derrick Johnson and safety Eric Berry after each missed most of last season due to injury. They were already one of the best defenses in the NFL last year, and now they’ll be even stronger in 2015. The Texans couldn’t do much on offense all game until the fourth quarter, when it was already decided.

Denver’s offense was atrocious against Baltimore in the opener. The Broncos did not score one offensive touchdown, and it’s clear that Peyton Manning is on the decline after a horrible finish to last season. Manning went 24-of-40 passing for 175 yards with an interception, which was returned for a touchdown. They only managed 69 rushing yards on 25 carries as well. Baltimore has a good defense, but it is not as good as the one Kansas City fields this season.

The Broncos are 0-5 ATS in their last five games following a ATS win. The Chiefs are 6-1 ATS in their last seven home games.

The Broncos are 0-5 ATS in their last five games following a ATS win. The Chiefs are 6-1 ATS in their last seven home games. Kansas City is 9-3 ATS in its last 12 vs. AFC opponents. The Chiefs are 4-0 ATS in their last four September games.